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The following questions would be answered in the conclusion -How do the enzymes

The following questions would be answered in the conclusion -How do the enzymes work (what are the mechanisms)? -How do these compare to mechanisms of other enzymes discussed in the lectures? -How is the pathway regulated? (This may not be known; make inferences and back up your position) - Does the pathway feed into glycolysis, or the TCA cycle, or some other pathway? -How much energy is generated (or used) in the pathway in terms of molecules such as ATP,…

I chose ( Spike protein for SARS-COV-2 )(5 pt) Why you were interested in examin

I chose ( Spike protein for SARS-COV-2 )(5 pt) Why you were interested in examining this particular gene?Part I. DNA & mRNA(2 pt) From NCBI, find the Chromosome and structure (5’ → 3’)(1 pt) Short list of homologues in other organisms (name and species)(1 pt) Additional gene names (1 pt) mRNA sequence (5’ → 3’)(3 pt) Use the ExPasy online tools to generate the 6 different potential open reading frames from a mRNA (cDNA) sequencePart II. Protein & domain motifs(2…

Regulation of protein stability and function by the ubiquitin-proteasome system

Regulation of protein stability and function by the ubiquitin-proteasome system (UPS) influences diverse aspects of eukaryotic biology. The ubiquitylation cascade involves three enzymes—E1, E2, and E3—that work successively to attach ubiquitin to substrate proteins, which results in altered protein function or proteasomal degradation. Substrate specificity is conferred by E3 ubiquitin ligases, of which the SCF family of cullin-RING ubiquitin ligases (CRLs) is among the most intensively studied. CAND1 interacts with Cullin–RING core complexes at both the N terminus, where it…

This week’s discussion will focus on the functions of transport proteins in the

This week's discussion will focus on the functions of transport proteins in the phospholipid bilayer of the plasma membrane including concepts of diffusion, facilitated diffusion, osmosis, and active transport, among other functions of membrane proteins (and lipids), with special emphasis on how malfunction of the transport proteins would affect health of The Cell. The following learning objectives should be achieved during your discussion: • Explain the primary functions of the plasma membrane. • Describe the structure of the phospholipid bilayer.…